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OBITUARY - Professor Konstanty Wiśniewski, MD, PhD (1935-2003). Włodzimierz Buczko (p. 1) Article (PDF format) REVIEW - Adrenomedullin - what do we know 10 years since its discovery? Jerzy Bełtowski, Anna Jamroz (p. 5) Abstract / Article (PDF format) REVIEW - Calcium modulation in epilepsy. Wojciech Kułak, Wojciech Sobaniec, Katarzyna Wojtal, Stanisław J. Czuczwar (p. 29) Abstract / Article (PDF format) REVIEW - Gamma-hydroxybutyric acid (GHB) and its chemical modifications: A review of the GHBergic system. Anna Waszkielewicz, Jacek Bojarski (p. 43) Abstract / Article (PDF format) Are glycineB sites involved in the development of morphine tolerance? Jolanta Kotlińska (p. 51) Abstract / Article (PDF format) Competitive NMDA receptor antagonists and agonist: Effects on spontaneous alternation in mice exposed to cerebral oligemia. Lucyna Jóźwiak, Krzysztof Łukawski, Stanisław J. Czuczwar, Maria Sieklucka-Dziuba (p. 59) Abstract / Article (PDF format) Allopurinol does not affect the anticonvulsant activity of carbamazepine and valproate in maximal electroshock-induced convulsions in mice. Jolanta Parada-Turska, Mirosław Czuczwar, Jacek Kiś, Piotr Czuczwar, Anna Cioczek, Jarogniew Łuszczki, Stanisław J. Czuczwar (p. 67) Abstract / Article (PDF format) Is anorexia in thioacetamide-induced cirrhosis related to an altered brain serotonin concentration? Saida Haider, Sadia Saleem, Saima Shameem, Shahida P. Ahmed, Tahira Parveen, Darakhshan J. Haleem (p. 73) Abstract / Article (PDF format) Monosodium glutamate affects the temporal characteristics of biochemical variables in Wistar rats. Thamilarasan Manivasagam, Perumal Subramanian (p. 79) Abstract / Article (PDF format) Attenuation of oxidative stress-induced changes in thalassemic erythrocytes by vitamin E. Nandita Das, Tapasi Das Chowdhury, Aindrila Chattopadhyay, Asoke G. Datta (p. 85) Abstract / Article (PDF format) Antithrombotic effect of captopril and enalapril in young rats. Włodzimierz Buczko, Andrzej Kubik, Iwona Kucharewicz, Ewa Chabielska (p. 97) Abstract / Article (PDF format) Influence of a new propranolol analogue on the rabbit myocardium in vitro. Edyta Olakowska, Marek Olakowski (p. 105) Abstract / Article (PDF format) In vitro induction of cytochrome P450 enzymes in hepatocytes isolated from the regenerating rat liver. Viola Támasi, Zsuzsanna Riedl, Ottó Dobozy, András Falus, László Vereczkey, Katalin Monostory (p. 113) Abstract / Article (PDF format) Glycine prevents hepatic fibrosis by preventing the accumulation of collagen in rats with alcoholic liver injury. Rajagopal Senthilkumar, Namasivayam Nalini (p. 121) Abstract / Article (PDF format) Immunophilin ligands decrease release of pro-inflammatory cytokines (IL-1beta TNF-alpha and IL-2) in rat astrocyte cultures exposed to simulated ischemia in vitro. Bożena Gabryel, Krzysztof Łabuzek, Andrzej Małecki, Zbigniew S. Herman (p. 129) Abstract / Article (PDF format) SHORT COMMUNICATION Intestinal absorption of digoxin and interaction with nimodipine in rats. Fatma S. Kilic, Özlem Batu, Başar Sirmagul, Engin Yildirim, Kevser Erol (p. 137) Abstract / Article (PDF format) Abstracts of Eighth Conference on PROGRESS IN ETIOPATHOGENESIS OF SEIZURES (p. 145) (PDF format)

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REVIEW - Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage. Russel J. Reiter, Dun-Xian Tan, Eloisa Gitto, Rosa M. Sainz, Juan C. Mayo, Josefa Leon, Lucien C. Manchester, Vijayalaxmi, Ertugrul Kilic, Ülkan Kilic (p. 159) Abstract / Article (PDF format) REVIEW - Genetic basis of neurodegeneration in familial Alzheimer’s disease. Anna Kowalska (p. 171) Abstract / Article (PDF format) Synergistic effect of imipramine and amantadine in the forced swimming test in rats. Behavioral and pharmacokinetic studies. Zofia Rogóż, Grażyna Skuza, Maciej Kuśmider, Jacek Wójcikowski, Marta Kot, Władysława A. Daniel (p. 179) Abstract / Article (PDF format) Riluzole enhances the antiseizure action of conventional antiepileptic drugs against pentetrazole-induced convulsions in mice. Kinga K. Borowicz, Andrzej Sękowski, Edyta Drelewska, Stanisław J. Czuczwar (p. 187) Abstract / Article (PDF format) A multicenter, placebo-controlled, double-blind study of efficacy of a new form of carbamazepine (Carbatrol(R)) in refractory epileptic patients. Wojciech Sobaniec, Wojciech Kułak, Joanna Śmigielska-Kuzia, Leszek Boćkowski, Jerzy Majkowski, Joanna Jędrzejczak (p. 195) Abstract / Article (PDF format) Receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide in the goose cerebral cortex. Jolanta B. Zawilska, Paweł Niewiadomski, Jerzy Z. Nowak (p. 203) Abstract / Article (PDF format) Up-regulation of renal Na+, K+-ATPase: the possible novel mechanism of leptin-induced hypertension. Jerzy Bełtowski, Anna Jamroz-Wiśniewska, Ewelina Borkowska, Grażyna Wójcicka (p. 213) Abstract / Article (PDF format) Central role of cAMP in the inhibition of glycogen breakdown and gluconeogenesis promoted by leptin and insulin in perfused rat liver. Glaucia R. Borba-Murad, Márcia Vardanega-Peicher, Sharize B. Galende, Rui Curi, Helenir M. Souza, Erica G. Mario, Bruna K. Bassoli, Roberto B. Bazotte (p. 223) Abstract / Article (PDF format) Role of an aminothiazole derivative on ethanol- and thermally oxidized sunflower oil-induced toxicity. Kode Aruna, Rajagopalan Rukkumani, Penumathsa Sureshvarma, Venugopal P. Menon (p. 233) Abstract / Article (PDF format) Protective effect of S-allylcysteine and lycopene in combination against N-methyl-N’-nitro-N-nitrosoguanidine-induced genotoxicity. Balaiya Velmurugan, Sathiyavedu T. Santhiya, Siddavaram Nagini (p. 241) Abstract / Article (PDF format) Ovine model for clear-cut study on the role of cholecystokinin in antral, small intestinal and gallbladder motility. Krzysztof W. Romański (p. 247) Abstract / Article (PDF format) Penetration of cotrimoxazole components into skin after a single oral dose. Theoretical versus experimental approach. Andrzej Królicki, Adam Klimowicz, Stanisława Bielecka-Grzela, Adam Nowak, Romuald Maleszka (p. 257) Abstract / Article (PDF format) SHORT COMMUNICATIONS Influence of selected cardiological drugs on oxidative status. Maria Kopff, Edward Kowalczyk, Anna Kopff (p. 265) Abstract / Article (PDF format) Losartan may prevent the elevation of plasma glucose levels induced by chronic stress. Yagíz Üresin, Bahar Erbaş, Mehmet Özek (p. 271) Abstract / Article (PDF format) PRELIMINARY COMMUNICATION Effect of topiramate on mechanical allodynia in neuropathic pain model in rats. Anna Wieczorkiewicz-Płaza, Pawel Płaza, Ryszard Maciejewski, Mirosław Czuczwar, Krzysztof Przesmycki (p. 275) Abstract / Article (PDF format)

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REVIEW - New generation of valproic acid. Michał K. Trojnar, Ewa Wierzchowska-Cioch, Maciej Krzyżanowski, Małgorzata Jargiełło, Stanisław J. Czuczwar (p. 283) Abstract / Article (PDF format) REVIEW - Is there any future for felbamate treatment? Kinga K. Borowicz, Barbara Piskorska, Żaneta Kimber-Trojnar, Robert Małek, Grzegorz Sobieszek, Stanisław J. Czuczwar (p. 289) Abstract / Article (PDF format) Potential antipsychotic and extrapyramidal effects of (R,S)-3,4-dicarboxyphenylglycine [(R,S)-3,4-DCPG], a mixed AMPA antagonist/mGluR8 agonist. Krystyna Ossowska, Małgorzata Pietraszek, Jadwiga Wardas, Stanisław Wolfarth (p. 295) Abstract / Article (PDF format) Antidepressants in chronic unpredictable mild stress (CUMS)-induced deficit of fighting behavior. Grażyna Ossowska, Zofia Danilczuk, Bożena Klenk-Majewska, Leszek Czajkowski, Iwona Żebrowska-Łupina (p. 305) Abstract / Article (PDF format) Statins rise cytoplasmic calcium level [Ca2+]i in cultured endothelial cells. Barbara Lorkowska, Stefan Chlopicki, Ewa Marcinkiewicz, Ryszard J. Gryglewski (p. 313) Abstract / Article (PDF format) Effect of antagonists of adrenergic and cholinergic receptors on ion transport in the isolated rabbit caecum wall. Danuta I. Kosik-Bogacka, Bolesław Banach, Tomasz Tyrakowski, Tomasz Czarny, Łukasz Jodko (p. 319) Abstract / Article (PDF format) Effect of etoposide on the processes of osseous tissue remodeling in rats. Urszula Cegieła, Joanna Folwarczna, Maria Pytlik, Waldemar Janiec (p. 327) Abstract / Article (PDF format) Effects of nadroparin on bone histomorphometric parameters in rats. Joanna Folwarczna, Waldemar Janiec, Maria Barej, Urszula Cegieła, Maria Pytlik, Ilona Kaczmarczyk-Sedlak (p. 337) Abstract / Article (PDF format) Effects of retinol on development of osteopenic changes induced by bilateral ovariectomy in rats. Maria Pytlik, Urszula Cegieła, Joanna Folwarczna, Waldemar Janiec, Wojciech Pytlik (p. 345) Abstract / Article (PDF format) SHORT COMMUNICATIONS Effect of sildenafil on anxiety in the plus-maze test in mice. Mehmet Kurt, Sirri S. Bilge, Elif Aksoz, Osman Kukula, Suleyman Celik, Yuksel Kesim (p. 353) Abstract / Article (PDF format) Preliminary phenotypic characterization of the Warsaw High Preferring (WHP) and Warsaw Low Preferring (WLP) lines of rats selectively bred for high and low ethanol consumption. Wanda Dyr, Wojciech Kostowski (p. 359) Abstract / Article (PDF format) 3alpha,7alpha-Dihydroxy-12-oxo-5beta-cholanate as blood-brain barrier permeator. Momir Mikov, Slavko Kevrešan, Ksenija Kuhajda, Vida Jakovljevič, Velibor Vasovič (p. 367) Abstract / Article (PDF format) Inhibition of DNA topoisomerase I and II, and growth inhibition of MDA-MB-231 human breast cancer cells by bis-benzimidazole derivatives with alkylating moiety. Krzysztof Bielawski, Sławomir Wołczyński, Anna Bielawska (p. 373) Abstract / Article (PDF format)

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Age-dependent effects of 5,7-dihydroxytryptamine on serotonin transporter in different brain areas in the rat. Wojciech Kostowski, Andrzej Bidziński, Paweł Krząścik, Janusz Szyndler, Paulina Rok, Paulina Kołomańska, Aleksandra Wisłowska, Małgorzata Lehner, Adam Płaźnik (p. 383) Abstract / Article (PDF format) Calcium channel antagonists attenuate cross-sensitization to the locomotor effects of nicotine and ethanol in mice. Grażyna Biała, Barbara Węglińska (p. 391) Abstract / Article (PDF format) Effect of chronic treatment with dexamethasone on brain dopamine receptors in mice. Andrzej Wróbel, Gabriel Nowak, Grażyna Ossowska, Zofia Danilczuk, Iwona Żebrowska-Łupina, Marian Wielosz (p. 399) Abstract / Article (PDF format) Pertussis toxin-sensitive G protein modulates the ability of histamine to stimulate cAMP production in the chick pineal gland. Jolanta B. Zawilska, Jolanta Rosiak, Jerzy Z. Nowak (p. 407) Abstract / Article (PDF format) Influence of dopamine on flash visual evoked potentials (FVEP) in prenatally mercury intoxicated rats. Ewa Herba, Dorota Pojda-Wilczek, Agata R. Plech, Stefan M. Pojda, Ryszard Szkilnik (p. 415) Abstract / Article (PDF format) Effect of different forms of vasoactive intestinal peptide on cyclic AMP formation in the mammalian cerebral cortex. Agnieszka Dejda, Hanna Gendek-Kubiak, Jerzy Z. Nowak (p. 421) Abstract / Article (PDF format) Preparation of cardiovascular disease-related genes microarray and its application in exploring ligustrazine-induced changes in endothelial gene expression. Li Zesong, Li Deliang, Huang Jian, Zhang Wen, Ding Yu, Wang Shengqi (p. 427) Abstract / Article (PDF format) Epirubicin HCl toxicity in human-liver derived hepatoma G2 cells. Aysun Ozkan, Kayahan Fişkin (p. 435) Abstract / Article (PDF format) Acetylator phenotyping in patients with malignant lymphomas, using caffeine as the metabolic probe. Basem M. William, Ahmed M. Abdel-tawab, Essam A. Hassan, Omar Fathy Mohamed (p. 445) Abstract / Article (PDF format) Effects of enoxaparin on histomorphometric parameters of bones in rats. Joanna Folwarczna, Waldemar Janiec, Marta Gawor, Maria Pytlik, Ilona Kaczmarczyk-Sedlak, Barbara Nowińska (p. 451) Abstract / Article (PDF format) SHORT COMMUNICATIONS SIB 1893, a selective mGluR5 receptor antagonist, potentiates the anticonvulsant activity of oxcarbazepine against amygdala-kindled convulsions in rats. Kinga K. Borowicz, Jarogniew J. Łuszczki, Stanisław J. Czuczwar (p. 459) Abstract / Article (PDF format) Effect of single and repeated in vitro exposure of ovarian follicles to o,p’-DDT and p,p’-DDT and their metabolites. Anna K. Wójtowicz, Ewa L. Gregoraszczuk, Anna Ptak, Jerzy Falandysz (p. 465) Abstract / Article (PDF format) Cytotoxic and proapoptotic effects of new Pd(II) and Pt(II)-complexes with 2-ethanimidoyl- 2-methoxy-2H-1,2-benzoxaphosphinin-4-ol-2-oxide. Elżbieta Budzisz, Urszula Krajewska, Marek Różalski (p. 473) Abstract / Article (PDF format) Pharmacokinetic interaction after joint administration of zinc and imipramine in forced swim test in mice. Elżbieta Wyska, Joanna Szymura-Oleksiak, Włodzimierz Opoka, Bogusław Baś, Ewa Niewiara, Lucyna Pomierny, Małgorzata Dybała, Gabriel Nowak (p. 479) Abstract / Article (PDF format) PRELIMINARY COMMUNICATIONS Influence of lovastatin on BCL-2 and BAX expression by plasma cells and T lymphocytes in short-term cultures of multiple myeloma bone marrow mononuclear cells. Anna Dmoszyńska, Monika Podhorecka, Jacek Roliński, Maria Soroka-Wojtaszko (p. 485) Abstract / Article (PDF format) Doxepin inhibits CYP2D6 activity in vivo. Monika Szewczuk-Boguslawska, Andrzej Kiejna, Jan A. Beszłej, Krystyna Orzechowska-Juzwenko, Piotr Milejski (p. 491) Abstract / Article (PDF format)

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REVIEW - Influence of the absolute configuration on pharmacological activity of antihypertensive and antiarrhythmic drugs. Katarzyna Kulig, Piotr Nowicki, Barbara Malawska (p. 499) Abstract / Article (PDF format) REVIEW - Neuroprotective role of testosterone in the nervous system. Magdalena Białek, Paweł Zaremba, Kinga K. Borowicz, Stanisław J. Czuczwar (p. 509) Abstract / Article (PDF format) Anxiolytic- and antidepressant-like effects of 7-OH-DPAT, preferential dopamine D3 receptor agonist, in rats. Zofia Rogóż, Grażyna Skuza, Aleksandra Kłodzińska (p. 519) Abstract / Article (PDF format) 2R,4R-APDC influence on hypoxia-induced impairment of learning and memory processes in passive avoidance test. Halina Car, Róża J. Wiśniewska, Konstanty Wiśniewski (p. 527) Abstract / Article (PDF format) Effect of nonselective and selective opioid receptors antagonists on antinociceptive action of acetaminophen [Part III]. Magdalena Bujalska (p. 539) Abstract / Article (PDF format) Influence of pre-operative ketoprofen administration (preemptive analgesia) on analgesic requirement and the level of prostaglandins in the early postoperative period. Włodzimierz Wnęk, Renata Zajączkowska, Jerzy Wordliczek, Jan Dobrogowski, Ryszard Korbut (p. 547) Abstract / Article (PDF format) Effect of topiramate on the kainate-induced status epilepticus, lipid peroxidation and immunoreactivity of rats. Marta Kubera, Bogusława Budziszewska, Lucylla Jaworska-Feil, Agnieszka Basta-Kaim, Monika Leśkiewicz, Magdalena Tetich, Michael Maes, Günter Kenis, Andrzej Marciniak, Stanisław J. Czuczwar, Grzegorz Jagła, Wojciech Nowak, Władysław Lasoń (p. 553) Abstract / Article (PDF format) Flupentixol and trifluperidol reduce interleukin-1beta and interleukin-2 release by rat mixed glial and microglial cell cultures. Jan Kowalski, Krzysztof Labuzek, Zbigniew S. Herman (p. 563) Abstract / Article (PDF format) Acetylator phenotyping in patients with malignant lymphomas, using caffeine as the metabolic probe. Maria Pytlik, Ilona Kaczmarczyk-Sedlak, Leszek Śliwiński, Waldemar Janiec, Igor Rymkiewicz (p. 571) Abstract / Article (PDF format) Modulatory effects of curcumin on lipid peroxidation and antioxidant status during nicotine-induced toxicity. Chandran Kalpana, Venugopal P. Menon (p. 581) Abstract / Article (PDF format) Influence of Casearia esculenta root extract on protein metabolism and marker enzymes in streptozotocin-induced diabetic rats. Annamalai Prakasam, Subramaniam Sethupathy, Kodukkur Viswanathan Pugalendi (p. 587) Abstract / Article (PDF format) SHORT COMMUNICATIONS Effect of MPEP, a selective mGluR5 antagonist, on the antielectroshock activity of conventional antiepileptic drugs. Marek Zadrożniak, Andrzej Sękowski, Stanisław J. Czuczwar, Kinga K. Borowicz (p. 595) Abstract / Article (PDF format) Effect of the nitric oxide donor and the nitric oxide synthase inhibitor on the liver of rats with chronic hepatitis induced by imethylnitrosamine. Oxana Lukivskaya, Ruslan Lis, Krzysztof Zwierz, Vyacheslav Buko (p. 599) Abstract / Article (PDF format) Effect of nitric oxide synthase inhibition on antinociceptive action of different doses of acetaminophen. Magdalena Bujalska (p. 605) Abstract / Article (PDF format) Pentoxifylline does not affect nociception if administered postoperatively. Antoni M. Szczepanik, Jerzy Wordliczek, Wojciech Serednicki, Maciej Siedlar, Antoni Czupryna (p. 611) Abstract / Article (PDF format) PRELIMINARY COMMUNICATION Participation of endogenous corticosteroids in inflammatory response in type 2 streptozotocin diabetic rats. Gessilda A. N. de Melo, Juliano L. Sartoretto, Silvana M. Caparroz-Assef, Ciomar A. Bersani-Amado, Zuleica B. Fortes, Roberto K.N. Cuman (p. 617) Abstract / Article (PDF format) POLISH-GERMAN CONFERENCE "NITROSATIVE STRESS AND ITS ROLE IN MECHANISM OF BRAIN AGING AND NEURODEGENERATIVE DISORDERS" ABSTRACTS (p. 625) (PDF format) PRELIMINARY COMMUNICATIONS Elevated nitric oxide production mediates beta-amyloid-induced mitochondria failure. Uta Keil, Astrid Bonert, Celio A. Marques, Joanna B. Strosznajder, Franz Müller-Spahn, Walter E. Müller, Anne Eckert (p. 631) Abstract / Article (PDF format) Cell cycle arrest induced in human breast cancer cells by cyclin-dependent kinase inhibitors: a comparison of the efects exerted by roscovitine and olomoucine. Józefa Węsierska-Gądek, Marieta Gueorguieva, Jacek Wojciechowski, Marcel Horky (p. 635) Abstract / Article (PDF format) Inhibition of nitric oxide synthase prevents energy failure and oxidative damage evoked in the brain by lipopolysaccharide. Grzegorz A. Czapski, Magdalena Cąkała, Dorota Kopczuk, Monika Kamińska, Joanna B. Strosznajder (p. 643) Abstract / Article (PDF format) Influence of the therapy with pergolide mesylate plus L-DOPA and with L-DOPA alone on serum cGMP level in PD patients. Małgorzata Chalimoniuk, Adam Stępień (p. 647) Abstract / Article (PDF format) Aging decreases phosphatidylinositol-4,5-bisphosphate level but has no effect on activities of phosphoinositide kinases. Agata Zambrzycka (p. 651) Abstract / Article (PDF format)

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REVIEW - Brain dopamine receptors - research perspectives and potential sites of regulation. Marta Dziedzicka-Wasylewska (p. 659) Abstract / Article (PDF format) REVIEW - Neurogenesis in the adult Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Markowicz-Kula, Krzysztof Wędzony (p. 673) Abstract / Article (PDF format) REVIEW - Apoptosis in the central nervous system: mechanisms and protective strategies. Małgorzata Kajta (p. 689) Abstract / Article (PDF format) REVIEW - Potential role of the brain dopaminergic system in the regulation of cytochrome P-450 expression. Jacek Wójcikowski (p. 701) Abstract / Article (PDF format) MPEP, mGlu5 receptor antagonist, regulates NPYmRNA expression in hippocampal and amygdalar neurons. Maria Śmiałowska, Joanna M. Wierońska, Piotr Brański, Ewa Obuchowicz, Andrzej Pilc (p. 709) Abstract / Article (PDF format) Involvement of nitricoxidergic system in the hypnotic effects of benzodiazepines in mice. Sylwia Talarek, Sylwia Fidecka (p. 719) Abstract / Article (PDF format) Inhibition of rodent brain monoamine oxidase and tyrosine hydroxylase by endogenous compounds - 1,2,3,4-tetrahydro-isoquinoline alkaloids. Antoni Patsenka, Lucyna Antkiewicz-Michaluk (p. 727) Abstract / Article (PDF format) Effects of joint administration of imipramine and amantadine in patients with drug-resistant unipolar depression. Zofia Rogóż, Marta Dziedzicka-Wasylewska, Władysława A. Daniel, Jacek Wójcikowski, Dominika Dudek, Andrzej Wróbel, Andrzej Zięba (p. 735) Abstract / Article (PDF format) New 4-[omega-(diarylmethylamino)alkyl]- and 4-[omega-(diarylmethoxy)alkyl]-1-arylpiperazines as selective 5-HT1a/5-HT2a receptor ligands with differentiated in vivo activity. Maria H. Paluchowska, Sijka Charakchieva-Minol, Ewa Tatarczyńska, Aleksandra Kłodzińska, Katarzyna Stachowicz, Ewa Chojnacka-Wójcik (p. 743) Abstract / Article (PDF format) Synthesis and cardiovascular activity of new 8-alkylamino-1,3-dimethyl-7-(2-hydroxy-3- piperazinopropyl)-3,7-dihydro-1H-purine-2,6-diones. Grażyna Chłoń-Rzepa, Maciej Pawłowski, Małgorzata Zygmunt, Barbara Filipek, Dorota Maciąg (p. 755) Abstract / Article (PDF format) Antiarrhythmic profile and endothelial action of novel decahydroquinoline derivatives. Valery I. Kozlovski , Vladimir P. Vdovichenko, Stefan Chłopicki, Sergey S. Malchik, Kaldybek D. Praliyev, Oral T. Zcilkibayev (p. 767) Abstract / Article (PDF format) Anti-inflammatory effects of selective COX-2 inhibitors. Halis Süleyman, Berna Demircan, Yalçín Karagöz, Nuray Öztaşan, Bahadír Süleyman (p. 775) Abstract / Article (PDF format) Effect of simvastatin and fluvastatin on plasma fibrinogen levels in patients with primary hypercholesterolemia. Bogusław Okopień, Robert Krysiak, Andrzej Madej, Dariusz Belowski, Marek Zieliński, Jan Kowalski, Zbigniew S. Herman (p. 781) Abstract / Article (PDF format) Hypoxic and pharmacological preconditioning preserves vasomotor response of porcine coronary artery. Jernej Kuzner, Gorazd Drevenšek, Borut Geršak, Metka Budihna (p. 789) Abstract / Article (PDF format) Role of adrenal gland hormones in the mechanism of antiulcer action of nimesulide and ranitidine. Halis Süleyman, Berna Demircan, Fatma Göçer, Zekai Halící, Ahmet Hacímüftüoglu (p. 799) Abstract / Article (PDF format) Changes and their regression in the osseous system in rats after administering a cytostatic drug inhibiting tumor cell division in the phase of DNA synthesis. Urszula Cegieła, Maria Pytlik, Waldemar Janiec (p. 805) Abstract / Article (PDF format) Effect of administration of alendronate sodium and retinol on the mechanical properties of the femur in ovariectomized rats. Leszek Śliwiński, Waldemar Janiec, Maria Pytlik, Joanna Folwarczna, Ilona Kaczmarczyk-Sedlak, Wojciech Pytlik, Urszula Cegieła, Barbara Nowińska (p. 817) Abstract / Article (PDF format) SHORT COMMUNICATIONS Effect of imipramine treatment on plasma dopamine beta-hydroxylase activity in chronic mild stress in rats. Mariola Grabowska, Małgorzata Schlegel-Zawadzka, Mariusz Papp, Gabriel Nowak (p. 825) Abstract / Article (PDF format) Chronic treatment with citalopram does not affect the expression of alpha1-adrenergic receptor (alpha1-ar) subtypes. Grzegorz Kreiner, Adam Bielawski, Agnieszka Zelek-Molik, Marta Kowalska, Irena Nalepa (p. 831) Abstract / Article (PDF format) Influence of antidepressant drugs on macrophage cytotoxic activity in rats. Dariusz Belowski, Jan Kowalski, Andrzej Madej, Zbigniew S. Herman (p. 837) Abstract / Article (PDF format) Introduction of a new complex imide system into the structure of LCAPs. The synthesis and a 5-HT1A, 5-HT2A and D2 receptor binding study. Jerzy Kossakowski, Aldona Raszkiewicz, Ryszard Bugno, Andrzej J. Bojarski (p. 843) Abstract / Article (PDF format) PRELIMINARY COMMUNICATIONS Effect of metyrapone supplementation on imipramine therapy in patients with treatment-resistant unipolar depression. Zofia Rogóż, Grażyna Skuza, Jacek Wójcikowski, Władysława A.Daniel, Andrzej Wróbel, Dominika Dudek, Andrzej Zięba (p. 849) Abstract / Article (PDF format) Effects of chronic treatment with classic and newer antidepressants and neuroleptics on the activity and level of CYP2D in the rat brain. Anna Haduch, Jacek Wójcikowski, Władysława A. Daniel. (p. 857) Abstract / Article (PDF format) Selective mGlu5 receptor antagonist MTEP attenuates naloxone-induced morphine withdrawal symptoms. Agnieszka Pałucha, Piotr Brański, Andrzej Pilc (p. 863) Abstract / Article (PDF format) Intraamygdaloid administration of BIBO 3304 increases water intake and extends anxiolytic effects. Joanna M. Wierońska, Katarzyna Stachowicz, Aleksandra Kłodzińska, Maria Śmiałowska, Andrzej Pilc (p. 867) Abstract / Article (PDF format) Influence of beta-adrenergic antagonists on tear secretion in children. Elżbieta Samochowiec-Donocik, Bronisława Koraszewska-Matuszewska (p. 871) Abstract / Article (PDF format)